Projects
- Effects of cardiorespiratory fitness, physical activity and sedentary behavior on insulin resistance among breast cancer survivors being treated with anti-estrogen endocrine therapies (COMIRB #21-3245). Breast cancer survivors treated with aromatase inhibitors and selective ER modulators (SERM) have an elevated risk for developing type 2 diabetes (T2D). It is unknown how cardiorespiratory fitness or other aspects of active and sedentary behaviors reduce the risk of T2D among breast cancer survivors treated with endocrine therapy. The purpose of this study is to explore the relationships between cardiorespiratory fitness, physical activity, sedentary behavior, and glucose tolerance/insulin sensitivity in women diagnosed with breast cancer and treated with aromatase inhibitors or SERMs. For more information or to see if you are eligible, email patplab@colostate.edu
- Fit Cancer. This is an outreach program that offers an evidence-based group exercise class exclusive to cancer survivors. One of the goals of this project is to determine best practices in delivering a group-based exercise program for cancer survivors in a community setting. To participate, call (970) 491-4653, email patplab@colostate.edu, or visit our website. CSU IRB#17-7067H
- An adaptive physical activity maintenance intervention for cancer survivors. Despite the success of interventions for increasing physical activity among cancer survivors, many survivors return to inactive or insufficiently active behaviors after the intervention ends. To facilitate long-term maintenance of physical activity, this study will test an adaptive intervention approach, which allocates additional support and resources to those who are having difficulty maintaining physical activity following the completion of an exercise program. For more information or to participate, call (970) 491-4653, or email patplab@colostate.edu. CSU IRB#1740
Recent and Selected Publications
- Leach HJ, Bolt M, Clark EW, Hull SE, Diamond JR, Lyden K, Scalzo RL. Cardiorespiratory fitness, physical activity, sedentary behavior, and diabetes risk among breast cancer survivors treated with endocrine therapies. Med Sci Sports Exer. 2025 Sep 1. doi: 10.1249/MSS.0000000000003849. Epub ahead of print.
- Gomes EL, Bell C, Marker RJ, Aichele S, Leach HJ. Acute effects of exercise to mitigate cancer-related fatigue: A state-of-the-art review. Euro J Cancer Care. 2025. Article ID 5511950
- Crisafio ME, Thraen-Borowski K, Schmitz KH, Leach HJ. A scoping review of videoconference exercise programs for cancer survivors in community settings. Translational Journal of the American College of Sports Medicine; 9 (2), Spring 2024.
- Leach HJ, Gomes EL, Hidde MC, Lyden K, Bryan AD, Cockburn MG, Messersmith WA. A videoconference physical activity intervention for colorectal cancer survivors: a pilot randomized controlled trial. OBM Integrative and Complementary Medicine 2023; 8(4): 060; doi:10.21926/obm.icm.230406
- Leach HJ, Fairman CM, Gomes EL, Marker RJ. Evaluating individual-level change in physical function response following an exercise program for cancer survivors. Support Care Cancer 31, 353 (2023).
- Leach HJ, Crisafio ME, Howell MJ, Nicklawsky A, Marker RJ. 2023. A Group-Based, Videoconference-Delivered Physical Activity Program for Cancer Survivors. Translational Journal of the ACSM. 8(2):e000221, Spring 2023